annexin V

General Information (Source: NCBI Gene,UniProt)

Text mining Term annexin V
UniProt ID ANXA5_RAT
Name PAP-I
Lipocortin V
Annexin V
Placental anticoagulant protein 4
PP4
Vascular anticoagulant-alpha
VAC-alpha
Anchorin CII
CBP-I
Placental anticoagulant protein I
Calphobindin I
Endonexin II
Annexin-5
Annexin A5
Thromboplastin inhibitor
Gene Names Anxa5
Synonyms:Anx5
Taxonomy Rattus norvegicus

General annotation

Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Subcellular location

Gene Ontology

GO:0005737 cytoplasm CC
GO:0005509 calcium ion binding MF
GO:0042383 sarcolemma CC
GO:0005544 calcium-dependent phospholipid binding MF
GO:0042995 cell projection CC
GO:0050819 negative regulation of coagulation BP
GO:0007596 blood coagulation BP
GO:0014704 intercalated disc CC
GO:0043065 positive regulation of apoptotic process BP
GO:0051260 protein homooligomerization BP
GO:0030971 receptor tyrosine kinase binding MF

Sequence

>gi|6978505|ref|NP_037264.1| annexin A5 [Rattus norvegicus]
MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSE
LTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVV
GDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDK
YMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLF
NIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD

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Database Cross Reference

Ensembl Gene
UniGene Rn.3318
PDB 2RAN
2H0M
1BC1
1N42
2H0K
1BC3
1BCW
2H0L
1BCZ
2IE7
2IE6
1BC0
1BCY
1N41
1G5N
1N44
1A8B
1A8A
RefSeq NP_037264.1
Pfam PF00191